Career

• 2022-now PostDoc at the University of Vienna, Department of Food Chemistry and Toxicology. Research group: Ass.Prof. Giorgia Del Favero,
  FWF project: Morpho-metabolic fingerprinting of ovarian cancer

• 2016-2022 Researcher/PhD student, Institute of Biophysics of the Czech Academy of Science, Brno ,CZ.
  Projects: Role of AhR in cellular metabolism, Advanced in vitro models of lung epithelial cells for analysis of airborne pollutants

Education

• 2016-2022 PhD in Animal Physiology and Immunology, Department of Experimental Biology - Faculty of Science - Masaryk University, CZ, Thesis: The cellular lipidome as diagnostic and predictive factor in normal and tumor cell populations

• 2014-2016 Magister in Molecular Biology and Genetics, Department of Experimental Biology - Faculty of Science - Masaryk University, CZ; Thesis: Adaptive plasticity and its effect on neuroblastoma chemotherapy

• 2011-2014 Bachelor in Molecular Biology and Genetics, Department of Experimental Biology - Faculty of Science - Masaryk University, CZ; Thesis: Epigenetics and tumors

Publications

• 10/2023 Gruber L., Jobst M., Kiss E., Karasová M., Englinger B., Berger W., Del Favero G., Intracellular remodeling associated with endoplasmic reticulum stress modifies biomechanical compliance of bladder cells, Cell Communication and Signaling

• 04/2023 Bergen J., Karasová M., Bileck A., Pignitter M., Marko D., Gerner Ch., Del Favero G., Exposure to dietary fatty acids oleic and palmitic acid alters structure and mechanotransduction of intestinal cells in vitro, Archives of Toxicology

• Aryl Hydrocarbon Receptor (AhR) Limits the Inflammatory Responses in Human Lung Adenocarcinoma A549 Cells via Interference with NF-κB Signaling.
  Vázquez-Gómez G, Karasová M, Tylichová Z, Kabátková M, Hampl A, Matthews J, Neča J, Ciganek M, Machala M, Vondráček J.Cells. 2022 Feb 17;11(4):707. doi: 10.3390/cells11040707.PMID: 35203356

• Inhibition of Aryl Hydrocarbon Receptor (AhR) Expression Disrupts Cell Proliferation and Alters Energy Metabolism and Fatty Acid Synthesis in Colon Cancer Cells.
  Karasová M, Procházková J, Tylichová Z, Fedr R, Ciganek M, Machala M, Dvořák Z, Vyhlídalová B, Zůvalová I, Ehrmann J, Bouchal J, Andrysík Z, Vondráček J.Cancers (Basel). 2022 Aug 31;14(17):4245. doi: 10.3390/cancers14174245.PMID: 36077780

Poster Presentations

• 03/2024 Karasova M., Framke D., Gerner Ch., Del Favero G., Response profile of mechanosensitive transcription factors YAP1 and Nrf2 after shear stress stimulation in ovarian cancer cell lines, 9th German Pharm-Tox Summit, Munich, Germany