Publications

2024

Del Favero G., Bergen J., Palm L., Fellinger Ch., Matlaeva M., Szabadi A., Fernandes A.S., Saraiva N., Schröder Ch., Marko D., Short-Term Exposure to Foodborne Xenoestrogens Affects Breast Cancer Cell Morphology and Motility Relevant for Metastatic Behavior In Vitro, Chemical Research in Toxicology, September 11, 2024, DOI: 10.1021/acs.chemrestox.4c00061

Jobst M., Crudo F., Di Franco J., Marko D., Cerbino R., Gerner C., Del Favero G., P13-32 Bafilomycin induces mitochondrial reorganization, nuclear deformation and γH2AX increase in T24 bladder cancer cells, Toxicology Letters, September 2024, DOI: 10.1016/j.toxlet.2024.07.548

Iriarte-Mesa C., Bergen J., Danielyan K., Crudo F., Marko D., Kählig H., Del Favero G., Kleitz F., Functionalization of Silica Nanoparticles for Tailored Interactions with Intestinal Cells and Chemical Modulation of Paracellular Permeability, Small Science, 01 August 2024, DOI: 10.1002/smsc.202400112

Skos L., Schmidt C., Thomas S.R., Park M., Geiger V., Wenisch D., Bonsignore R., Del Favero G., Mohr Th., Bileck A., Gerner Ch., Casini A., Meier-Menches S.M., Gold-templated covalent targeting of the CysSec-dyad of thioredoxin reductase 1 in cancer cells, Cell Reports Physical Science, July 17, 2024, DOI: 10.1016/j.xcrp.2024.102072

Hohagen M., Saraiva N., Kählig H., Gerner C., Del Favero G., Kleitz F., Silica nanoparticle conjugation with gallic acid towards enhanced free radical scavenging capacity and activity on osteosarcoma cells in vitro, Journal of Materials Chemistry B, May 16, 2024, DOI: 10.1039/d4tb00151f

Brynzak-Schreiber E., Schögl E., Bapp C., Klaudia Cseh K., Kopatz V., Jakupec M.A., Weber A., Lange T., Toca-Herrera J.L., Del Favero G., Wadsak W., Kenner L., Pichler V., Microplastics role in cell migration and distribution during cancer cell division, Chemosphere, April 2024, DOI: 10.1016/j.chemosphere.2024.141463

Hohagen M., Sánchez L., Herbst A-J., Kählig H., Won Shin J., Berry D., Del Favero G., Kleitz F., MANNosylation of Mesoporous Silica Nanoparticles Modifies TLR4 Localization and NF-κB Translocation in T24 Bladder Cancer Cells, Advanced Healthcare Matererials, 2024 Mar 30, DOI: 10.1002/adhm.202304150, Online ahead of print.

Crudo F., Dellafiora L., Hong Ch., Burger L., Jobst M., Del Favero G., Marko D., Combined in vitro and in silico mechanistic approach to explore the potential of Alternaria mycotoxins alternariol and altertoxin II to hamper γH2AX formation in DNA damage signaling pathways, Toxicology Letters, 2024 Feb 23, DOI: 10.1016/j.toxlet.2024.02.008. Online ahead of print.

Varga E., Prause H-Ch., Riepl M., Hochmayr N., Berk D., Attakpah E., Kiss E., Medić N., Del Favero G., Ostenfeld Larsen Th., Hansen P.J., Marko D., Cytotoxicity of Prymnesium parvum extracts and prymnesin analogs on epithelial fish gill cells RTgill-W1 and the human colon cell line HCEC-1CT, Archives of Toxicology, 2024 Jan 11, DOI: 10.1007/s00204-023-03663-5. Online ahead of print.

Jobst M., Hossain M., Kiss E., Bergen J., Marko D., Del Favero G., Autophagy modulation changes mechano-chemical sensitivity of T24 bladder cancer cells, Biomedicine & Pharmacotherapy, Volume 170, January 2024, DOI: 10.1016/j.biopha.2023.115942

2023

Riva A., Rasoulimehrabani H., Cruz-Rubio J.M., Schnorr S.L., Von Baeckmann C., Inan D., Nikolov G., Herbold C.W., Hausmann B., Pjevac P., Schintlmeister A., Spittler A., Palatinszky M., Kadunic A., Hieger N., Del Favero G., Von Bergen M., Jehmlich N., Watzka M., Lee K.S., Wiesenbauer J., Khadem S., Viernstein H., Stocker R., Wagner M., Kaiser Ch., Richter A., Kleitz F., Berry D., Identification of inulin-responsive bacteria in the gut microbiota via multi-modal activity-based sorting, nature communications, 2023 Dec 14, DOI: 10.1038/s41467-023-43448-z.

Crudo F., Hong Ch., Varga E., Del Favero G., Marko D., Genotoxic and Mutagenic Effects of the Alternaria Mycotoxin Alternariol in Combination with the Process Contaminant Acrylamide, Toxins, Nov. 24, 2023, DOI: 10.3390/toxins15120670

Gruber L., Jobst M., Kiss E., Karasová M., Englinger B., Berger W., Del Favero G., Intracellular remodeling associated with endoplasmic reticulum stress modifies biomechanical compliance of bladder cells, Cell Communication and Signaling, Oct. 30, 2023, DOI: 10.1186/s12964-023-01295-x

Janker J., Schuster D., Bortel P., Hagn G., Meier-Menches S.M., Mohr T., Mader J.C., Slany A., Bileck A., Brunmair J., Madl C., Unger L., Hennlich B., Weitmayr B., Del Favero G., Pils D., Pukrop T., Pfisterer N., Feichtenschlager T., Gerner C., Multiomics-empowered Deep Phenotyping of Ulcerative Colitis Identifies Biomarker Signatures Reporting Functional Remission States, Journal of Crohn's and Colitis, Volume 17, Issue 9, September 2023, DOI: 10.1093/ecco-jcc/jjad052

Iriarte-Mesa C., Jobst M. Bergen J., Kiss E., Ryoo R., Kim J.-C., Crudo F., Marko D., Kleitz F., Del Favero G., Morphology-Dependent Interaction of Silica Nanoparticles with Intestinal Cells: Connecting Shape to Barrier Function, Nano Letters, July 11, 2023, DOI: 10.1021/acs.nanolett.3c00835 

Buchacher T., Digruber A., Kanzler M., Del Favero G., Ehling-Schulz M., Bacillus cereus extracellular vesicles act as shuttles for biologically active multicomponent enterotoxins, Cell Communication and Signaling, 2023 May 15, DOI: 10.1186/s12964-023-01132-1

Bergen J., Karasova M., Bileck A., Pignitter M., Marko D., Gerner Ch., Del Favero G., Exposure to dietary fatty acids oleic and palmitic acid alters structure and mechanotransduction of intestinal cells in vitro, Archives of Toxicology, April 29, 2023, DOI:10.1007/s00204-023-03495-3

Hlaoperm Ch., Sudjarwo W.A.A., Ehrenbrandtner J., Kiss E., Del Favero G., Choowongkomon K., Rattanasrisomporn J., Lieberzeit P.A., Molecularly Imprinted Nanoparticle Ensembles for Rapidly Identifying S. epidermidis, Sensors, 2023 Mar 28, DOI: 10.3390/s23073526.

Janker L., Schuster D., Bortel P., Hagn G., Meier-Menches S., Mohr Th., Mader J.C., Slany A., Bileck A., Brunmair J., Madl Ch., Unger L., Hennlich B., Weitmayr B., Del Favero  G., Pils D., Pukrop T., Pfisterer N., Feichtenschlager Th., Gerner Ch., Multi-omics empowered deep phenotyping of ulcerative colitis identifies biomarker signatures reporting functional remission states, Journal of Crohn´s and Colitis, 2023 Mar 24, DOI: 10.1093/ecco-jcc/jjad052. Online ahead of print.

2022

Peña B., Gao S., Borin D., Del Favero G., Abdel-Hafiz M., Farahzad N., Lorenzon P., Sinagra G., Taylor M.R.G., Mestroni L., Sbaizero O., Cellular Biomechanic Impairment in Cardiomyocytes Carrying the Progeria Mutation: An Atomic Force Microscopy Investigation, Langmuir, Nov. 24, 2022, DOI: 10.1021/acs.langmuir.2c02623

Aichinger G., Pahlke G., Puntscher H., Groestlinger J., Grabher S., Braun D., Tillmann K., Plasenzotti R., Del Favero G., Warth B., Höger H., Marko D., Markers for DNA damage are induced in the rat colon by the Alternaria toxin altertoxin-II, but not a complex extract of cultured Alternaria alternata, Frontiers in Toxicology, Oct. 24, 2022, DOI: 10.3389/ftox.2022.977147

Jobst M., Kiss E., Gerner Ch., Marko D., Del Favero G., Activation of autophagy triggers mitochondrial loss and changes acetylation profile relevant for mechanotransduction in bladder cancer cells, Archives of Toxicology, October 10, 2022, DOI: 10.1007/s00204-022-03375-2

Del Favero G., Jobst M., Kiss E., Marko D., P12-25 Response profile of bladder cells to environmental stressors: how modulation of autophagy reflects on biomechanical compliance, Toxicology Letters, Volume 368, Supplement, Sept. 1, 2022, Page S184, DOI: org/10.1016/j.toxlet.2022.07.504

Rebhahn V.I.Ch., Kiss E., Marko D., Del Favero G., Foodborne compounds that alter plasma membrane architecture can modify the response of intestinal cells to shear stress in vitro, Toxicology and Applied Pharmacology, Volume 446, 1 July 2022, DOI: 10.1016/j.taap.2022.116034

Groestlinger J., Seidl C., Varga E., Del Favero G., Marko D., Combinatory Exposure to Urolithin A, Alternariol, and Deoxynivalenol Affects Colon Cancer Metabolism and Epithelial Barrier Integrity in vitro, Frontiers in Nutrition, June 24, 2022, DOI: 10.3389/fnut.2022.882222

Hohagen M., Guggenberger P., Kiss E., Kählig H., Marko D., Del Favero G., Kleitz F., TANNylation of Mesoporous Silica Nanoparticles and Bioactivity Profiling in Intestinal Cells, Journal of Colloid and Interface Science, May 10, 2022, DOI: 10.1016/j.jcis.2022.05.035

Von Baeckmann C., Riva A., Guggenberger P., Kählig H., Won Han S., Inan D., Del Favero G., Berry D., Kleitz F., Targeting Gut Bacteria Using Inulin-Conjugated Mesoporous Silica Nanoparticles, Advanced Materials Interfaces, April 17, 2022, DOI: 10.1002/admi.202102558

Groestlinger J., Spindler V., Pahlke G., Rychlik M., Del Favero G., Marko D., Alternaria alternata Mycotoxins Activate the Aryl Hydrocarbon Receptor and Nrf2-ARE Pathway to Alter the Structure and Immune Response of Colon Epithelial Cells, ACS Chemical Research in Toxicology, April 11, 2022, DOI: 10.1021/acs.chemrestox.1c00364

Crudo F., Aichinger G., Dellafiora L., Kiss E., Mihajlovic J., Del Favero G., Berry D., Dall’Asta Ch., Marko D., Persistence of the antagonistic effects of a natural mixture of Alternaria mycotoxins on the estrogen-like activity of human feces after anaerobic incubation, Toxicology Letters, Vol 358, April 2022, DOI: 10.1016/j.toxlet.2022.01.015

Bileck A., Bortel P., Kriz M., Janker L., Kiss E., Gerner Ch., Del Favero G., Inward Outward Signaling in Ovarian Cancer: Morpho-Phospho-Proteomic Profiling Upon Application of Hypoxia and Shear Stress Characterizes the Adaptive Plasticity of OVCAR-3 and SKOV-3 Cells, frontiers in Oncology, 14 February 2022 | DOI: 10.3389/fonc.2021.746411

Beisl J., Pahlke G., Ehling-Schulz M., Del Favero G., Marko D., Cereulide and Deoxynivalenol Increase LC3 Protein Levels in HepG2 Liver Cells, Toxins, Feb. 18, 2022, DOI: 10.3390/toxins14020151

2021

Del Favero G., Aichinger G., Hohenbichler J., Marko D., Dall’Asta Ch., Dellafiora L., A target fishing study to spot possible biological targets of fusaric acid: Inhibition of protein kinase-A and insights on the underpinning mechanisms, Food and Chemical Toxicology, Nov. 5, 2021, DOI: 10.1016/j.fct.2021.112663

Flasch M., Bueschl Ch., Del Favero G., Adam G., Schuhmacher R., Marko D., Warth B., Elucidation of xenoextrogen metabolism by non-targeted, stable isotope-assisted mass spetremotry in breast cancer cells, Environmental International, volume 158, Oct. 12, 2021, DOI: 10.1016/j.envint.2021.106940

Rusz M., Del Favero G., El Abiead Y., Gerner C., Keppler B., Jakupec M., Koellensperger G., Morpho-metabotyping the oxidative stress respons, Scientific Reports, 2021 Jul 29;11(1):15471. doi: 10.1038/s41598-021-94585-8

Aichinger G., Del Favero G., Warth B., Marko D., Alternaria toxins-Still emerging? Comprehensive Reviews in Food Science and Food Safety, 2021 Jul 29. doi: 10.1111/1541-4337.12803. Online ahead of print

Brunmair J., Bileck A., Stimpfl T., Raible F., Del Favero G., Meier-Menches SM., Gerner C., Metabo-tip: a metabolomics platform for lifestyle monitoring supporting the development of novel strategies in predictive, preventive and personalised medicine, EMPA J., 2021 May 4;12(2):141-153. doi: 10.1007/s13167-021-00241-6. eCollection 2021 Jun.

Del Favero G., Zeugswetter M., Kiss E., Marko D., Endoplasmic Reticulum Adaptation and Autophagic Competence Shape Response to Fluid Shear Stress in T24 Bladder Cancer Cells, frontiers in Pharmacology, 03 May 2021, DOI: 10.3389/fphar.2021.647350

Del Favero G., Janker L., Neuditschko B., Hohenbichler J., Kiss E., Woelflingseder L., Gerner Ch., Marko D., Exploring the dermotoxicity of the mycotoxin deoxynivalenol: combined morphologic and proteomic profiling of human epidermal cells reveals alteration of lipid biosynthesis machinery and membrane structural integrity relevant for skin barrier function, Archives of Toxicology, 2021 Apr. 1, doi: 10.1007/s00204-021-03042-y

Beisl J., Varga E., Braun D., Warth B., Ehling-Schulz M., Del Favero G., Marko D., Assessing Mixture Effects of Cereulide and Deoxynivalenol on Intestinal Barrier Integrity and Uptake in Differentiated Human Caco-2 Cells, Toxins, 2021 March, DOI: 10.3390/toxins13030189

Niederstaetter L., Neuditschko B., Brunmair J., Janer L., Bileck A., Del Favero G., Gerner Ch., Eicosanoid Content in Fetal Calf Serum Accounts for Reproducibility Challenges in Cell Culture, Biomolecules, 2021 Jan 15;11(1):113. doi: 10.3390/biom11010113.

2020

Meier-Menches S.M., Neuditschko B., Zappe K., Schaier M., Gerner M.C., Schmetterer K.G., Del Favero G., Bonsignore R., Cichna-Markl M., Koellensperger G., Casini A., Gerner Ch., An Organometallic Gold(I) Bis-N-Heterocyclic Carbene Complex with Multimodal Activity in Ovarian Cancer Cells, Chemistry, 2020 Dec 1;26(67):15528-15537. doi: 10.1002/chem.202003495

Del Favero G., Bonifacio A., Rowland T. J., Gao Sh., Song K., Sergo V., Adler E. D., Mestroni L., Sbaizero O., Taylor M. R. G., Danon Disease-Associated LAMP-2 Deficiency Drives Metabolic Signature Indicative of Mitochondrial Aging and Fibrosis in Cardiac Tissue and hiPSC-Derived Cardiomyocytes, Journal of Clinical Medicine, 2020 Jul 31;9(8):E2457. doi: 10.3390/jcm90824

Hohenbichler J., Aichinger G., Rychlik M., Del Favero G., Marko D., Alternaria alternata Toxins Synergistically Activate the Aryl Hydrocarbon Receptor Pathway In Vitro, Biomolecules 2020, 10(7), 1018, July 9, 2020, DOI: 10.3390/biom10071018

Juère E., Del Favero G., Masse F., Marko D., Popat A., Florek J., Caillard R., Kleitz F., Gastro-protective protein-silica nanoparticles formulation for oral drug delivery: in vitro release, cytotoxicity and mitochondrial activity, European Journal of Pharmaceutics and Biopharmaceutics, 2020 June. pii: S0939-6411(20)30082-5. doi: 10.1016/j.ejpb.2020.03.015

Aichinger G., Dellafiora L., Pantazi F., Del Favero G., Galaverna G., Dall'Asta C., Marko D., Alternaria toxins as casein kinase 2 inhibitors and possible consequences for estrogenicity: a hybrid in silico/in vitro study, Archives of Toxicology, 2020 June, doi: 10.1007/s00204-020-02746-x

Gerner M.C., Ziegler L.S., Schmidt R.L.J., Krenn M., Zimprich F., Uyanik-Ünal K., Konstantopoulou V., Derdak S., Del Favero G., Schwarzinger I., Boztug K., Schmetterer K.G., The TGF-b/SOX4 axis and ROS-driven autophagy co-mediate CD39 expression in regulatory T-cells, FASEB Journal, 2020 June, doi: 10.1096/fj.201902664

Del Favero G., Kraegeloh A., Integrating Biophysics in Toxicology, Cells, 2020 May 21;9(5):E1282. doi: 10.3390/cells9051282

Juère E., Caillard R., Marko D., Del Favero G., Kleitz F., Smart protein-based formulation of dendritic mesoporous silica nanoparticles: Toward oral delivery of insulin, Chemistry, 2020 Apr. 21. doi: 10.1002/chem.202000773

Aichinger G., Lichtenberger F.B., Steinhauer T.N., Flörkemeier I., Del Favero G., Clement B., Marko D., The Aza-Analogous Benzo[c]phenanthridine P8-D6 Acts as a Dual Topoisomerase I and II Poison, thus Exhibiting Potent Genotoxic Properties, Molecules. 2020 Mar 27;25(7). pii: E1524. doi: 10.3390/molecules25071524.

Del Favero G., Mayer R.M., Dellafiora L., Janker L., Niederstaetter L., Dall'Asta C., Gerner C., Marko D., Structural Similarity with Cholesterol Reveals Crucial Insights into Mechanisms Sustaining the Immunomodulatory Activity of the Mycotoxin Alternariol, Cells, 2020 Mar 31;9(4). pii: E847. doi: 10.3390/cells9040847

Beisl J., Pahlke G., Abeln H., Ehling-Schulz M., Del Favero G., Varga E., Warth B., Sulyok M., Abia W., Ezekiel CN., Marko D., Combinatory effects of cereulide and deoxynivalenol on in vitro cell viability and inflammation of human Caco-2 cells, Archives of Toxicology, 2020 March, doi: 10.1007/s00204-020-02658-w

Neuditschko B., Janker L., Niederstaetter L., Brunmair J., Krivanek K., Izraely S., Sagi-Assif O., Meshel T., Keppler B., Del Favero G., Witz I.P., Gerner C., The challenge of classifying metastatic cell properties by molecular profiling exemplified with cutaneous melanoma cells and their cerebral metastasis from patient derived mouse xenografts, Molecular & Cellular Proteomics, March 2020, pii: mcp.RA119.001886. doi: 10.1074/mcp.RA119.001886

Muqaku B., Pils D., Mader J.C., Aust S., Mangold A., Muqaku L., Slany A., Del Favero G., Gerner Ch., Neutrophil extracellular trap formation correlates with improved overall survival in ovarian cancer, Cancers (Basel), 2020 Feb 21;12(2). pii: E505. doi: 10.3390/cancers12020505.

Del Favero G., Hohenbichler J., Mayer R.M., Rychlik M., Marko D., Mycotoxin Altertoxin II Induces Lipid Peroxidation Connecting Mitochondrial Stress Response to NF-κB Inhibition in THP-1 Macrophages, Chemical Research in Toxicology, 2020 Feb, doi: 10.1021/acs.chemrestox.9b00378

2019

Costa J.G., Vidovic B., Saraiva N., do Céu Costa M., Del Favero G., Marko D., Oliveira N.G., Fernandes A.S., Contaminants: a dark side of food supplements? Free Radical Research, 2019 Sep 10:1-23. doi: 10.1080/10715762.2019.1636045

Del Favero, G.; Bialas, F.; Grabher-Wusche, S.; Wittig, A.; Bräuer, B.; Gerthsen, D.; Echalier, C.; Kamalov, M.; Marko, D.; Becker, Ch.F.W.; Silica particles with a Quercetin-R5 peptide conjugate are taken up into HT-29 cells and translocate into the nucleus, Chemical Communications, Aug, 2019, DOI: 10.1039/C9CC02215E

Gerner, M.C.; Niederstaetter, L.; Ziegler, L.; Bileck, A.; Slany, A.; Janker, L.; Schmidt, R.L.J.; Gerner, Ch.; Del Favero, G.; Schmetterer, K.G.; Proteome Analysis Reveals Distinct Mitochondrial Functions Linked to Interferon Response Patterns in Activated CD4+ and CD8+ T Cells, frontiers in pharmacology, July 10 2019, doi.org/10.3389/fphar.2019.00727

Wernitznig, D.; Kiakos, K.; Del Favero, G.; Harrer, N.; Machat, H.; Osswald, A.; Jakupec, M. A.; Wernitznig, A.; Sommergruber, W.; Keppler, B. K., First-in-class ruthenium anticancer drug (KP1339/IT-139) induces an immunogenic cell death signature in colorectal spheroids in vitro. Metallomics. 2019 Jun 19;11(6):1044-1048. doi: 10.1039/c9mt00051h.

Puntscher, H.; Hankele, S.; Tillmann, K.; Attakpah, E.; Braun, D.; Kutt, M. L.; Del Favero, G.; Aichinger, G.; Pahlke, G.; Hoger, H.; Marko, D.; Warth, B., First insights into Alternaria multi-toxin in vivo metabolism. Toxicology letters 2019 Feb;301:168-178. doi: 10.1016/j.toxlet.2018.10.006.

 

2018

Del Favero, G.; Zaharescu, R.; Marko, D., Functional impairment triggered by altertoxin II (ATXII) in intestinal cells in vitro: cross-talk between cytotoxicity and mechanotransduction. Archives of toxicology, Dec. 2018, doi:10.1007/s00204-018-2317-6 (2018).

Woelflingseder, L.; Del Favero, G.; Blazevic, T.; Heiss, E. H.; Haider, M.; Warth, B.; Adam, G.; Marko, D., Impact of glutathione modulation on the toxicity of the Fusarium mycotoxins deoxynivalenol (DON), NX-3 and butenolide in human liver cells. Toxicology letters, Dec. 2018,  doi:10.1016/j.toxlet.2018.09.007 (2018).

Del Favero, G.; Woelflingseder, L.; Braun, D.; Puntscher, H.; Kutt, M. L.; Dellafiora, L.; Warth, B.; Pahlke, G.; Dall'Asta, C.; Adam, G.; Marko, D., Response of intestinal HT-29 cells to the trichothecene mycotoxin deoxynivalenol and its sulfated conjugates. Toxicology letters, Oct. 2018, 295, 424-437. doi:10.1016/j.toxlet.2018.07.007.

Miklosi, A. G.; Del Favero, G.; Marko, D.; Harkany, T.; Lubec, G., Resolution Matters: Correlating Quantitative Proteomics and Nanoscale-Precision Microscopy for Reconstructing Synapse Identity. Proteomics, Jul 2018, 18 (14), e1800139 doi:10.1002/pmic.201800139.

Del Favero, G.; Woelflingseder, L.; Janker, L.; Neuditschko, B.; Seriani, S.; Gallina, P.; Sbaizero, O.; Gerner, C.; Marko, D., Deoxynivalenol induces structural alterations in epidermoid carcinoma cells A431 and impairs the response to biomechanical stimulation. Scientific reports, Jul 27, 2018, 8 (1), 11351. doi:10.1038/s41598-018-29728-5.

Miklosi, A. G.; Del Favero, G.; Bulat, T.; Hoger, H.; Shigemoto, R.; Marko, D.; Lubec, G., Super-resolution Microscopical Localization of Dopamine Receptors 1 and 2 in Rat Hippocampal Synaptosomes. Molecular neurobiology, Jun 2018, 55 (6), 4857-4869. doi:10.1007/s12035-017-0688-y.

Dellafiora, L.; Warth, B.; Schmidt, V.; Del Favero, G.; Mikula, H.; Frohlich, J.; Marko, D., An integrated in silico/in vitro approach to assess the xenoestrogenic potential of Alternaria mycotoxins and metabolites. Food chemistry, May 2018, 248, 253-261. doi:10.1016/j.foodchem.2017.12.013.

 

2017

Wittig, A.; Gehrke, H.; Del Favero, G.; Fritz, E. M.; Al-Rawi, M.; Diabate, S.; Weiss, C.; Sami, H.; Ogris, M.; Marko, D., Amorphous Silica Particles Relevant in Food Industry Influence Cellular Growth and Associated Signaling Pathways in Human Gastric Carcinoma Cells. Nanomaterials (Basel, Switzerland), Jan 2017, 7 (1). doi:10.3390/nano7010018.

Jarolim, K.; Del Favero, G.; Ellmer, D.; Stark, T. D.; Hofmann, T.; Sulyok, M.; Humpf, H. U.; Marko, D., Dual effectiveness of Alternaria but not Fusarium mycotoxins against human topoisomerase II and bacterial gyrase. Archives of toxicology, Apr 2017, 91 (4), 2007-2016. doi:10.1007/s00204-016-1855-z.

Jarolim, K.; Del Favero, G.; Pahlke, G.; Dostal, V.; Zimmermann, K.; Heiss, E.; Ellmer, D.; Stark, T. D.; Hofmann, T.; Marko, D., Activation of the Nrf2-ARE pathway by the Alternaria alternata mycotoxins altertoxin I and II. Archives of toxicology, Jan 2017, 91 (1), 203-216. doi:10.1007/s00204-016-1726-7.

 

2016

Warth, B.; Del Favero, G.; Wiesenberger, G.; Puntscher, H.; Woelflingseder, L.; Fruhmann, P.; Sarkanj, B.; Krska, R.; Schuhmacher, R.; Adam, G.; Marko, D., Identification of a novel human deoxynivalenol metabolite enhancing proliferation of intestinal and urinary bladder cells. Scientific reports, Sept 2016, 6, 33854. doi:10.1038/srep33854.

Seriani, S.; Del Favero, G.; Mahaffey, J.; Marko, D.; Gallina, P.; Long, C. S.; Mestroni, L.; Sbaizero, O., The cell-stretcher: A novel device for the mechanical stimulation of cell populations. The Review of scientific instruments, Aug 2016, 87 (8), 084301. doi:10.1063/1.4959884.

 

2015

Lanzicher, T.; Martinelli, V.; Puzzi, L.; Del Favero, G.; Codan, B.; Long, C. S.; Mestroni, L.; Taylor, M. R.; Sbaizero, O., The Cardiomyopathy Lamin A/C D192G Mutation Disrupts Whole-Cell Biomechanics in Cardiomyocytes as Measured by Atomic Force Microscopy Loading-Unloading Curve Analysis. Scientific reports 2015, 5, 13388. doi:10.1038/srep13388.

Schroeter, A.; Groh, I. A.; Del Favero, G.; Pignitter, M.; Schueller, K.; Somoza, V.; Marko, D., Inhibition of topoisomerase II by phase II metabolites of resveratrol in human colon cancer cells. Molecular nutrition & food research 2015, 59 (12), 2448-59. doi:10.1002/mnfr.201500352.

Perkin, J.; Slater, R.; Del Favero, G.; Lanzicher, T.; Hidalgo, C.; Anderson, B.; Smith, J. E.; Sbaizero, O.; Labeit, S.; Granzier, H., Phosphorylating Titin's Cardiac N2B Element by ERK2 or CaMKIIdelta Lowers the Single Molecule and Cardiac Muscle Force. Biophysical journal 2015, 109 (12), 2592-601. doi:10.1016/j.bpj.2015.11.002.

Lanzicher, T.; Martinelli, V.; Long, C. S.; Del Favero, G.; Puzzi, L.; Borelli, M.; Mestroni, L.; Taylor, M. R.; Sbaizero, O., AFM single-cell force spectroscopy links altered nuclear and cytoskeletal mechanics to defective cell adhesion in cardiac myocytes with a nuclear lamin mutation. Nucleus (Austin, Tex.) 2015, 6 (5), 394-407. doi:10.1080/19491034.2015.1084453.

Sbaizero, O.; DelFavero, G.; Martinelli, V.; Long, C. S.; Mestroni, L., Analysis of long- and short-range contribution to adhesion work in cardiac fibroblasts: an atomic force microscopy study. Materials science & engineering. C, Materials for biological applications 2015, 49, 217-224. doi:10.1016/j.msec.2014.12.083.

Seriani, S.; Del Favero, G.; Martinelli, V.; Mestroni, L.; Long, C.; Sbaizero, O.; Gallina, P., Quantification of Dual Reporter Cell Cultures via Image Analysis. 2015; Vol. 4, p 350-367.

 

2014

Del Favero, G., S. Sosa, M. Poli, A. Tubaro, O. Sbaizero, and P. Lorenzon. 2014. In vivo and in vitro effects of 42-hydroxy-palytoxin on mouse skeletal muscle: structural and functional impairmentToxicol Lett 225 (2):285-93. doi: 10.1016/j.toxlet.2013.12.020.

Codan, B., G. Del Favero, V. Martinelli, C. S. Long, L. Mestroni, and O. Sbaizero. 2014. Exploring the elasticity and adhesion behavior of cardiac fibroblasts by atomic force microscopy indentation. Mater Sci Eng C Mater Biol Appl 40:427-34. doi: 10.1016/j.msec.2014.04.003.

 

2009-2013

Del Favero, G., D. Beltramo, M. Sciancalepore, P. Lorenzon, T. Coslovich, M. Poli, E. Testai, S. Sosa, and A. Tubaro. 2013. "Toxicity of palytoxin after repeated oral exposure in mice and in vitro effects on cardiomyocytes."  Toxicon 75:3-15. doi: 10.1016/j.toxicon.2013.06.003.

Del Favero, G., S. Sosa, M. Pelin, E. D'Orlando, C. Florio, P. Lorenzon, M. Poli, and A. Tubaro. 2012. "Sanitary problems related to the presence of Ostreopsis spp. in the Mediterranean Sea: a multidisciplinary scientific approach."  Ann Ist Super Sanita 48 (4):407-14. doi: Doi: 10.4415/ann_12_04_08.

Del Favero, G., C. Florio, B. Codan, S. Sosa, M. Poli, O. Sbaizero, J. Molgo, A. Tubaro, and P. Lorenzon. 2012. "The stretch-activated channel blocker Gd(3+) reduces palytoxin toxicity in primary cultures of skeletal muscle cells."  Chem Res Toxicol 25 (9):1912-20. doi: 10.1021/tx300203x.

Tubaro, A., G. Del Favero, D. Beltramo, M. Ardizzone, M. Forino, M. De Bortoli, M. Pelin, M. Poli, G. Bignami, P. Ciminiello, and S. Sosa. 2011. "Acute oral toxicity in mice of a new palytoxin analog: 42-hydroxy-palytoxin."  Toxicon 57 (5):755-63. doi: 10.1016/j.toxicon.2011.02.009.

Tubaro, A., P. Durando, G. Del Favero, F. Ansaldi, G. Icardi, J. R. Deeds, and S. Sosa. 2011. "Case definitions for human poisonings postulated to palytoxins exposure."  Toxicon 57 (3):478-95. doi: 10.1016/j.toxicon.2011.01.005.

Baumgartner, L., S. Sosa, A. G. Atanasov, A. Bodensieck, N. Fakhrudin, J. Bauer, G. Del Favero, C. Ponti, E. H. Heiss, S. Schwaiger, A. Ladurner, U. Widowitz, R. D. Loggia, J. M. Rollinger, O. Werz, R. Bauer, V. M. Dirsch, A. Tubaro, and H. Stuppner. 2011. "Lignan derivatives from Krameria lappacea roots inhibit acute inflammation in vivo and pro-inflammatory mediators in vitro."  J Nat Prod 74 (8):1779-86. doi: 10.1021/np200343t.

Giangaspero, A., C. Ponti, F. Pollastro, G. Del Favero, R. Della Loggia, A. Tubaro, G. Appendino, and S. Sosa. 2009. "Topical anti-inflammatory activity of Eupatilin, a lipophilic flavonoid from mountain wormwood ( Artemisia umbelliformis Lam.)."  J Agric Food Chem 57 (17):7726-30. doi: 10.1021/jf901725p.

Sosa, S., G. Del Favero, M. De Bortoli, F. Vita, M. R. Soranzo, D. Beltramo, M. Ardizzone, and A. Tubaro. 2009. "Palytoxin toxicity after acute oral administration in mice."  Toxicol Lett 191 (2-3):253-9. doi: 10.1016/j.toxlet.2009.09.009.