Maximilian Jobst

Career

• Since 09/2022 PhD thesis

• 2022 Master Thesis “Authophagy activators and inhibitors in the modulation of mechanotransduction of T24 bladder cancer cells”

• 2019-2022 Master´s program "Food Chemistry" at the University of Vienna

• 2019 Bachelor Thesis "Characterization of immunoprecipitates for the analysis of biomarker candidates"

Publications

• 09/2024 Jobst M., Crudo F., Di Franco J., Marko D., Cerbino R., Gerner C., Del Favero G., P13-32 Bafilomycin induces mitochondrial reorganization, nuclear deformation and γH2AX increase in T24 bladder cancer cells, Toxicology Letters

• 02/2024 Crudo F., Dellafiora L., Hong Ch., Burger L., Jobst M., Del Favero G., Marko D., Combined in vitro and in silico mechanistic approach to explore the potential of Alternaria mycotoxins alternariol and altertoxin II to hamper γH2AX formation in DNA damage signaling pathways, Toxicology Letters

• 01/2024 Jobst M., Hossain M., Kiss E., Bergen J., Marko D., Del Favero G., Autophagy modulation changes mechano-chemical sensitivity of T24 bladder cancer cells, Biomedicine & Pharmacotherapy

• 10/2023 Gruber L., Jobst M., Kiss E., Karasová M., Englinger B., Berger W., Del Favero G., Intracellular remodeling associated with endoplasmic reticulum stress modifies biomechanical compliance of bladder cells, Cell Communication and Signaling

• 07/2023 Iriarte-Mesa C., Jobst M. Bergen J., Kiss E., Ryoo R., Kim J.-C., Crudo F., Marko D., Kleitz F., Del Favero G., Morphology-Dependent Interaction of Silica Nanoparticles with Intestinal Cells: Connecting Shape to Barrier Function, Nano Letters

• 10/2022 Jobst M., Kiss E., Gerner Ch., Marko D., Del Favero G., Activation of autophagy triggers mitochondrial loss and changes acetylation profile relevant for mechanotransduction in bladder cancer cells, Archives of Toxicology

Poster Presentations

• Jobst M., Crudo F., Di Franco J., Marko D., Cerbino R., Gerner Ch., Favero G.: Bafilomycin induces mitochondrial reorganization, nuclear deformation and γH2AX increase in T24 bladder cancer cells, 4. DoSChem Symposium, 12-13. September 2024, Vienna, Austria

• Jobst M., Crudo F., Di Franco J., Marko D., Cerbino R., Gerner Ch., Favero G.: Bafilomycin induces mitochondrial reorganization, nuclear deformation and γH2AX increase in T24 bladder cancer cells, EUROTOX 2024, 8-11 September 2024, Copenhagen, Denmark

• Jobst M., Bergen J., Kiss E., Marko D., Del Favero G.: In depth mitochondrial profiling reveals early signs of toxicity after exposure to deoxynivalenol and fusaric acid in bladder cancer cells, 45. Mycotoxin Workshop, June 3-5, 2024, Vienna, Austria

• 04/2024 Jobst M., Houssain M., Marko D., Del Favero G., "Techniques for mitochondrial image analysis for toxicity profiling of deoxynivalenol and fusaric acid in T24 bladder cancer cells", DoSChem Panel B Retreat, Röjtökmuzsaj, Hungary

• 04/2023 Jobst M., Hossain M., Kiss E., Del Favero G.: “Alternative Modes of Mitochondrial Toxicity: Multimodal Localization Of Mitochondria And Metabolic Markers”, DoSChem Retreat Panel B, Fürstenfeld, Austria

• 09/2022 Jobst M., Kiss E., Gerner Ch., Marko D., Del Favero G., Exploring Toxicological Implications for Krüppel-like Factors, ASTOX Symposium, Vienna, Austria

• 09/2022 Del Favero G., Jobst M., Kiss E., Marko D., P12-25 Response profile of bladder cells to environmental stressors: how modulation of autophagy reflects on biomechanical compliance, Toxicology Letters