Zeiss LSM 710 Laser Scanning Confocal Microscope

Confocal Laser Scanning Microscope from Zeiss 710 including the ELYRA system PS.1 for super-resolution microscopy. The LSM 710 allows the acquisition of 4 colors confocal images, SR-SIM images (also in 3D) and PALM/dSTORM images. The microscope is completed with temperature/CO2-controlled incubator for live cell imaging. Moreover, an additional set-up dedicated to image analysis is available to ensure high data-processing capacity.

Key technical features:

-Confocal system integrated with ELYRA system PS.1 for superresolution.

-Available Objectives for high resolution and live-cell imaging such as:

Alpha Plan-Apochromat 100x/1.46 Oil DIC M27 Elyra / Plan-Apochromat 63x/1.4 Oil DIC M27 / Water Plan-Apochromat 63x/1.0

-AndoriXon 897 back-thinned EM-CCD camera (Andor)

-Software: ZEN (black edition) 2.3 system

Application examples:

Buchacher T., Digruber A., Kanzler M., Del Favero G., Ehling-Schulz M., Bacillus cereus extracellular vesicles act as shuttles for biologically active multicomponent enterotoxins, Cell Communication and Signaling, 2023 May 15, DOI: 10.1186/s12964-023-01132-1

Von Baeckmann C., Riva A., Guggenberger P., Kählig H., Won Han S., Inan D., Del Favero G., Berry D., Kleitz F., Targeting Gut Bacteria Using Inulin-Conjugated Mesoporous Silica Nanoparticles, Advanced Materials Interfaces, April 17, 2022, DOI: 10.1002/admi.202102558

Miklosi, A. G.; Del Favero, G.; Bulat, T.; Hoger, H.; Shigemoto, R.; Marko, D.; Lubec, G., Super-resolution Microscopical Localization of Dopamine Receptors 1 and 2 in Rat Hippocampal Synaptosomes. Molecular neurobiology, Jun 2018, 55 (6), 4857-4869. doi:10.1007/s12035-017-0688-y.